Farnaz Moslemi; Sousan Rasooli; Marjan Dehdilani; Homayoun Sadeghi-Bazargani; Mahnaz Dehdilani
Volume 20, Issue 7 , 2018, Pages 1-9
Abstract
Background: Pain after laparoscopy may still be moderate to severe due to stretching of the intraabdominal cavity and peritoneal inflammation. Systemic Lidocaine with anti-inflammatory properties may reduce this pain.Objectives: The aim of this study was to evaluate the effect of perioperative intravenous ...
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Background: Pain after laparoscopy may still be moderate to severe due to stretching of the intraabdominal cavity and peritoneal inflammation. Systemic Lidocaine with anti-inflammatory properties may reduce this pain.Objectives: The aim of this study was to evaluate the effect of perioperative intravenous infusion of Lidocaine on postoperative pain relief after the gynecologic laparoscopic procedure. Methods: A double-blind, randomized clinical trial study was conducted in Iran, during the years 2014 and 2015. A sample of 60 females with American anesthesiology association (ASA) physical class I or II, who were scheduled for gynecologic laparoscopy wereselected through consecutive sampling and were randomly assigned to receive either intravenous Lidocaine or Normal saline, as placebo, prior to induction of anesthesia and until the end of surgery. The severity of postoperative pain was evaluated starting at the recovery unit until 24-hours postoperatively for a total of 8 times using the visual analogue scale (VAS) scoring system. Time to first analgesic request, total analgesic dose used in the first 24-hours, and any probable postoperative complications were recorded. Risk ratio (RR) and number needed to treat (NNT) were used to analyze the data along with the generalized linear model for multivariate analysis of repeated measurements over time.Results: The VAS at recovery was lower at recovery with a mean score of 2.8 in the Lidocaine group versus 3.9 in the control group (P = 0.02). Results of generalized linear modeling revealed that pain intensity decreased over time in both groups (P = 0.02), and the groups had different trend slopes in pain intensity over repeated measurements at various time points up to 24 hours after laparoscopy, while controlling for the baseline VAS at recovery and ASA PS (P = 0.016). However, when controlling for use of the pain- killers, the trends were not found to be different. Patients in the Lidocaine group were 3.8 times more likely not to need postoperative analgesic (95% CI: 1.4 to 9.9). Mean total analgesic dose was 1.3 mg in the Lidocaine group versus 38.2 mg in the control group differing significantly between the 2 groups (P < 0.01). Use of Lidocaine was associated with lower postoperative nausea and agitation. Conclusions: Systemic perioperative Lidocaine could improve the pain pattern and severity as well as nausea and agitation aftergynecologic laparoscopy. Although no significant side effects were detected in this study, the benefits of the intervention should be weighed against its safety.
Homayoun Sadeghi-Bazargani; Bahram Samadirad; Mina Golestani
Volume 19, Issue 4 , April 2017, , Pages 1-2
Abstract
The agricultural industry is one of the most hazardous industries. The combination of causes in the agricultural industry determines the potential to damage (1).
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The agricultural industry is one of the most hazardous industries. The combination of causes in the agricultural industry determines the potential to damage (1).
Saber Azami-Aghdash; Hassan Abolghasem Gorji; Homayoun Sadeghi-Bazargani; Hosein Shabaninejad
Volume 19, Issue 1 , January 2017, , Pages 1-12
Abstract
Background: Road traffic injuries (RTIs) are the leading cause of injuries and the second cause of mortality in Iran.Objectives: The aim of this study was to investigate the epidemiological pattern of RTIs in Iran based on the data from disaster management information system (DMIS) of the Iranian Red ...
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Background: Road traffic injuries (RTIs) are the leading cause of injuries and the second cause of mortality in Iran.Objectives: The aim of this study was to investigate the epidemiological pattern of RTIs in Iran based on the data from disaster management information system (DMIS) of the Iranian Red Crescent.Methods: In this cross-sectional study, the pattern of RTIs in Iran was studied based on the data from DMIS in the period from 20 March 2012 to 19 February 2016 (35 months). All of the 78775 RTIs recorded were selected through census. Data analysis was done using the SPSS.16 software package. P value less than 0.05 was considered statistically significant.Results: Among the 19 types of accidents whose data are recorded, road traffic accidents with a 78775 number of occurrence (136.1 ± 86.5 per 100000 people), 186860 injuries (332.1 ± 220 per 100000 people) and 12596 deaths (22.6 ± 11.1 per 100000 people) were the highest in ranking. The most common annunciator of the accidents was the emergency. Receiving the first report of the rescue operation was most done by telephone. The mean number of the operational forces involved in RTIs per 100000 people was 529.2 ± 407. The results showed that there was a significant difference between high, moderate and low population rate provinces in the mean number of injuries cases, the mortality of RTIs and the total number of Red Crescent operational forces (P < 0.05).Conclusions: Considering the high occurrence of the mortality and the injuries of the RTIs compared to that of the other types of accidents, more attention to RTIs in planning and interventions seems necessary.
